My research is in the areas of energetics, stability, subunit association and other factors that define the process by which a disordered protein chain attains its unique three-dimensional structure. By making use of ancient computational methods such as CHARMM, AMBER, and DEDUCTIVE REASONING I plan to add a factor of predictability to the three-dimensional structure of proteins in the near future. The current research investigates the energetics leading to the formation of homotypic helical bundles such as the Cartilage Oligomeric Matrix Protein (COMP).